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ALOXE3-nEDD

Previously: Lamellar ichthyosis, CIE, ARCI

nEDD Gene: ALOXE3 AR

Onset: Birth

Pathway: Lipid synthesis and transport

Category Paper: nEDD Paper

ALOXE3-nEDD: diffuse moderate scaling on the trunk.

Key Clinical Clues

Generalized mild scaling, collodion membrane at birth in some patients, sometimes self-improving.

References

Jobard F, Lefèvre C, Karaduman A et al. Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1. Hum Mol Genet 2002; 11:107-13.

Summarised from published literature for general information. This is not medical advice, and entries are still being verified. Read the full disclaimer