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KRT1-pEDD

Previously: Epidermolytic PPK

pEDD Gene: KRT1 AD, AR

Onset: Infancy

Pathway: Structural Proteins

Category Paper: pEDD Paper

KRT1-pEDD: diffuse plantar keratoderma.

Key Clinical Clues

Diffuse PPK, may be flexural involvement.

Additional Cutaneous Features

Histopathology: Epidermolytic hyperkeratosis/granular degeneration.

References

Terron-Kwiatkowski A, Terrinoni A, Didona B et al. Atypical epidermolytic palmoplantar keratoderma presentation associated with a mutation in the keratin 1 gene. Br J Dermatol 2004; 150:1096-103.

Summarised from published literature for general information. This is not medical advice, and entries are still being verified. Read the full disclaimer